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n-PROPANOL

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It is the by-product of aldolization and hydrogenation reaction between acryl alcohol and carbon monoxide and hydrogen. It is a kind of medium volatile colorless liquid with the odor of alcohols, soluble in water, alcohols and ethers.

CategoryDetails
Chemical FormulaCH₃CH₂CH₂OH
Key Applications– Solvents: Coatings, inks
– Intermediates: Esters/ethers synthesis
– Disinfectants: Hospital-grade sanitizers
– Food Grade: Flavor extracts
Physical Properties– Boiling Point: 97.2°C
– Flash Point: 15°C (closed cup)
– Miscibility: Fully soluble in water
– Vapor Pressure: 4.4kPa @20°C
Safety Parameters– NFPA Ratings: Health=1, Flammability=3, Reactivity=0
– Exposure Limits: TWA 200ppm (OSHA)
– Ingestion Hazards: Central nervous system depression
– Storage: Cool, well-ventilated area
Environmental Profile– Biodegradability: 96% (OECD 301F)
– Aquatic LC50: >100mg/L (Daphnia)
– Global Warming Potential: Low (no significant contribution)
– Waste Treatment: Biological wastewater plants
Quality Standards– Purity: ≥99.5% (GC analysis)
– Impurities: Water <0.2%, Isopropanol <0.1%
– Color: APHA <10
Market Dynamics– Demand Drivers: Pharmaceutical APIs, eco-friendly solvents
– Price Volatility: Linked to crude oil/natural gas feedstocks
– Sustainability Trends: Bio-based production via fermentation
Regulatory Compliance– REACH: Registered under 01-2119457575-38
– TSCA: Listed on Inventory
– Food Contact: FDA 21 CFR §175.300 compliant

Note: Balancing cost-effectiveness with growing environmental regulations. Emerging as preferred solvent in green chemistry applications due to ready biodegradability.

Physical & Chemical Properties

PropertySpecification
Molecular FormulaC₃H₈O
Boiling Point97°C
Density0.803 g/cm³ (20°C)
Flash Point22°C (closed cup)
SolubilityFully miscible with most organic solvents

Comparison with C1-C4 Alcohols

AlcoholCarbon AtomsBoiling Point (°C)Main Application
Methanol164.7Fuel, formaldehyde
Ethanol278.4Beverages, disinfectants
n-Propanol397.0Solvent, pharmaceuticals
n-Butanol4117.7Coatings, plasticizers

Industrial Applications

Major Uses

IndustryApplicationKey Benefit
PharmaceuticalsExtraction solventLow toxicity profile
Printing InksCarrier solventControlled evaporation rate
Cleaning ProductsDegreasing formulationsEffective oil removal
CosmeticsLotions and perfumesGood skin tolerance
Chemical SynthesisEster productionHigh reaction yield

Safety & Handling

Flammability: Class IB flammable liquid (NFPA)

Health Effects: Mild irritant (eyes/skin); high exposure may cause drowsiness

Storage: Keep in tightly sealed containers away from heat sources

Environmental: Readily biodegradable (BOD5/COD = 0.65)

Production Methods

Oxo Process (major industrial route)

Hydrogenation of Propionaldehyde

Fermentation (emerging bio-based production)

Conclusion

n-Propanol’s versatile solvent properties and favorable safety profile ensure its continued importance across industries. Future developments may focus on sustainable production methods and expanded pharmaceutical applications.

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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