2-Pentanone oxime

C5H11NO

2-Pentanone Oxime Technical Overview

2-Pentanone oxime (CAS 1192-28-5) is an organic compound widely used as an anti-skinning agent in paints and as an intermediate in chemical synthesis. Below are its key characteristics and applications.

1. General Properties of 2-Pentanone Oxime

2. Primary Applications and Performance

3. Handling and Safety Considerations

2-Pentanone oxime offers effective anti-skinning properties while maintaining good compatibility with various paint systems. Its relatively low toxicity makes it a preferred choice in many industrial applications.

Applications:

Coating industry

2-Pentanone oxime, with the chemical formula C5H11NO, is an organic compound belonging to the oxime class. It is derived from the reaction of 2-pentanone (a ketone) with hydroxylamine (NH2OH), where the carbonyl group (C=O) is replaced by an oxime group (C=NOH).

Physical Properties

2-Pentanone oxime is typically a colorless or pale yellow liquid with a distinctive odor. It has a boiling point of approximately 150-155°C and a density of around 0.9 g/cm³. It is soluble in various organic solvents, such as ethanol and ether, but has limited solubility in water.

Chemical Properties

1. Reduction: 2-Pentanone oxime can be reduced to the corresponding amine, such as 2-aminopentane.

2. Hydrolysis: Under acidic conditions, it can hydrolyze to regenerate 2-pentanone and hydroxylamine.

3. Stability：It is relatively stable at room temperature but may decompose when exposed to strong acids, bases, or high temperatures.

Applications

1. Organic Synthesis: It serves as an intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals.

2. Analytical Chemistry: It is used for the detection and quantification of carbonyl compounds.

3. Corrosion Inhibition: In some industrial settings, it is employed as a corrosion inhibitor for metals.

Safety and Storage

2-Pentanone oxime is moderately toxic and can be irritating to the skin and respiratory system. Proper protective equipment, such as gloves and goggles, should be worn during handling. It should be stored in a cool, well-ventilated area, away from heat sources and oxidizing agents.

Summary

2-Pentanone oxime is a versatile organic intermediate with applications in organic synthesis, analytical chemistry, and corrosion inhibition. While useful, its toxicity and reactivity require careful handling and storage.

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